Primary membranous nephropathy (MN) is a rare autoimmune cause of kidney failure. This dataset is from a genome-wide association study (GWAS) designed to identify novel genetic risk loci for MN. The provided cohort (named as European-1 Cohort) is composed of 611 cases of primary MN and 1,246 healthy controls of European ancestry. This cohort was used in the GWAS meta-analysis, as described in the manuscript entitled "Genetic architecture of membranous nephropathy and its potential diagnostic implications" (Nature Communications 2020, in press).The genome-wide summary statistics, including trans-ethnic meta-analysis across 8 GWAS cohorts of European and East Asian ancestry and ethnicity specific meta-analyses, are freely available for download on the Kiryluk lab website: <a href="http://www.columbiamedicine.org/divisions/kiryluk/resources.php">http://www.columbiamedicine.org/divisions/kiryluk/resources.php</a>.

GWAS for Membranous Nephropathy

1 selected publication including "The genetic architecture of membranous nephropathy and its potential t..." (176 citations)

GWAS for Membranous Nephropathy

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis