<p>This observational study was designed to determine the cellular tropism of Influenza A and B Viruses (IAV, IBV) from samples taken from the upper respiratory tract collected during routine nasal washes during the 2017-2018 season. Using single-cell RNA sequencing (scRNA-seq) we sought to determine which cell types could be infected, what the cellular response was to infection in both infected and bystander cells, and to compare the intra/inter-host variability of IAV and IBV during a single season at a single healthcare provider location.</p>

scRNA-Seq Analysis of Influenza Infected Upper Airway Patient Samples

Influenza, Human study with RNA-Seq, RNA Seq (NGS) data on dbGaP (18 participants)

scRNA-Seq Analysis of Influenza Infected Upper Airway Patient Samples

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Summary