Genome-Wide Association Study of Genetic Susceptibility for Graft-vs-Host Disease Cohort 1

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Anthropometry (4)

BMI - Recipient BMI (kg/m2) (phv00481967.v2.p1)
BMI_CAT - Recipient BMI, categorized: Children under 2 are "normal", children 2-20 are "underweight" if below the 5th percentile, "normal" if between 5-85th percentiles, "overweight" if between 85 and 95th percentiles, and "obese" if >=95th percentile. Adults categorized such that <18.5 is "underweight", 18.5-24.99 is "normal", 25 - 29.99 is "overweight", and >=30 is "obese". Missing BMI values are categorized as "normal" (phv00481968.v2.p1)
HTPR - Recipient height in cm (phv00481965.v2.p1)
WTPR - Recipient actual weight in kg (phv00481966.v2.p1)

Demographics (7)

AGE - Recipient age (phv00481939.v2.p1)
AGE_CAT - Recipient age (phv00481940.v2.p1)
DNRAGE - Donor age (phv00481941.v2.p1)
DNRAGE - Donor age (phv00481933.v2.p1)
DNRSEX - Donor gender (phv00481932.v2.p1)
SEX - Patient sex (phv00481942.v2.p1)
SEX - Biological Sex (phv00491907.v2.p1)

Disease Events (55)

AGVHD24 - Grade II-IV acute GVHD anytime post-BMT (phv00481994.v2.p1)
AGVHD34 - Grade III-IV acute GVHD anytime post-BMT (phv00481996.v2.p1)
ALIVERH1 - Acute GVHD, max liver involvement (phv00482006.v2.p1)
ALSTATPR - ALL disease status prior to transplant (phv00481950.v2.p1)
ALWGUTH1 - Acute GVHD, max lower intestinal tract involvement (phv00482004.v2.p1)
AMSTATPR - AML disease status prior to transplant (phv00481949.v2.p1)
ASKINH1 - Acute GVHD, max severity of skin involvement (phv00482003.v2.p1)
AUPGUTH1 - Acute GVHD, max upper intestinal tract involvement (phv00482005.v2.p1)
CGAUTH1 - Chronic GVHD, autoantibodies (phv00482018.v2.p1)
CGBRONH1 - Chronic GVHD, bronchiolitis obliterans (phv00482011.v2.p1)
CGEOSIH1 - Chronic GVHD, eosinophillia (phv00482017.v2.p1)
CGEYEH1 - Chronic GVHD, Eye involvement (phv00482009.v2.p1)
CGGIH1 - Chronic GVHD, gastrointestinal tract involvement (phv00482013.v2.p1)
CGLIVH1 - Chronic GVHD, liver involvement (phv00482014.v2.p1)
CGMOUH1 - Chronic GVHD, mouth involvement (phv00482010.v2.p1)
CGMUSKH1 - Chronic GVHD, musculoskeletal involvement (phv00482015.v2.p1)
CGOHEMH1 - Chronic GVHD, other hematologic involvement (phv00482019.v2.p1)
CGOLUNH1 - Chronic GVHD, other lung involvement (phv00482012.v2.p1)
CGOSKIH1 - Chronic GVHD, other skin or hair involvement (phv00482008.v2.p1)
CGOTHOH1 - Chronis GVHD, other organ involvement (phv00482022.v2.p1)
CGSCLEH1 - Chronic GVHD, sclerosis of skin (phv00482007.v2.p1)
CGSEROH1 - Chronic GVHD, serositis (phv00482020.v2.p1)
CGTHROH1 - Chronic GVHD, thrombocytopenia (phv00482016.v2.p1)
CGVHD - Chronic GVHD anytime post-BMT (phv00482000.v2.p1)
CGWTLOH1 - Chronic GVHD, weight loss (phv00482021.v2.p1)
DISEASE - Diagnosis (phv00481945.v2.p1)
DISTATAML_ALL - Disease status prior to transplant in AML and ALL patients (phv00481952.v2.p1)
DISTATD - Disease status prior to transplant, calculated from "distatgp2", where "Intermediate" cases are placed in "Early" category (phv00481948.v2.p1)
DISTATD_AML_ALL - Disease status prior to transplant in AML and ALL patients, where "intermediate" is categorized as "early" (phv00481953.v2.p1)
DISTATGP - Disease status prior to transplant (phv00481946.v2.p1)
DISTATGP2 - Disease status prior to transplant, calculated from "distatgp" (phv00481947.v2.p1)
DTHPRIM - Primary cause of death reported by center (phv00482023.v2.p1)
DTHPRIM2 - Second cause of death reported by center (phv00482025.v2.p1)
DTHPRIM3 - Third cause of death reported by center (phv00482027.v2.p1)
DTHPRIM4 - Fourth cause of death reported by center (phv00482029.v2.p1)
DTHPRIM5 - Fifth cause of death reported by center (phv00482031.v2.p1)
DTHPRIM6 - Sixth cause of death reported by center (phv00482033.v2.p1)
DTHPRIM7 - Seventh cause of death reported by center (phv00482035.v2.p1)
DWOAGVHD24 - Death without Grade II-IV acute GVHD anytime post-BMT (phv00481995.v2.p1)
DWOAGVHD34 - Death without Grade III-IV acute GVHD anytime post-BMT (phv00481997.v2.p1)
DWOCGVHD - Death wihtout chronic GVHD anytime post-BMT (phv00482001.v2.p1)
LFS_1Y - Relapse or death before 1 year post-BMT (phv00481992.v2.p1)
LFS_OVERALL - Leukemia-free survival overall- anytime post-BMT (phv00481988.v2.p1)
MDSTATPR - MDS disease status prior to transplant (phv00481951.v2.p1)
REL_1Y - Relapse before 1 year post-BMT (phv00481990.v2.p1)
REL_OVERALL - Relapse post-BMT (phv00481986.v2.p1)
TCCOD1GEN - Primary cause of death reported by center, grouped (phv00482024.v2.p1)
TCCOD2GEN - Second cause of death reported by center, grouped (phv00482026.v2.p1)
TCCOD3GEN - Third cause of death reported by center, grouped (phv00482028.v2.p1)
TCCOD4GEN - Fourth cause of death reported by center, grouped (phv00482030.v2.p1)
TCCOD5GEN - Fifth cause of death reported by center, grouped (phv00482032.v2.p1)
TCCOD6GEN - Sixth cause of death reported by center, grouped (phv00482034.v2.p1)
TCCOD7GEN - Seventh cause of death reported by center, grouped (phv00482036.v2.p1)
TRM_1Y - Transplant related mortality before 1 year post-BMT (phv00481991.v2.p1)
TRM_OVERALL - Transplant related mortality post-BMT (phv00481987.v2.p1)

Medications (2)

ATGCAMPATHGP - ATG or Campath (phv00481963.v2.p1)
GVHDGP - GVHD prophylaxis (phv00481962.v2.p1)

Race and Ethnicity (4)

DNRETHGP - Donor ethnicity (phv00481935.v2.p1)
DNRRACEGP - Donor race (phv00481934.v2.p1)
ETHGP - Recipient ethnicity (phv00481944.v2.p1)
RACEGP - Recipient race (phv00481943.v2.p1)

Other (46)

ABOTYPED - Donor ABO blood type (phv00481936.v2.p1)
ABOTYPER - Recipient ABO blood type (phv00481972.v2.p1)
ANALYTE_TYPE - Analyte type of sample (phv00482039.v2.p1)
BODY_SITE - Collection site of sample (phv00482038.v2.p1)
CONDINT - Conditioning intensity (phv00481975.v2.p1)
CONDLIST - Detailed list of all regimens (phv00481979.v2.p1)
CONSENT - Consent group as determined by DAC (phv00481926.v2.p1)
DEAD_1Y - Death before 1 year post-BMT (phv00481984.v2.p1)
DEAD_OVERALL - Survival status - overall at any timepoint post-BM (phv00481982.v2.p1)
DISTATMDS - Disease status prior to transplant in MDS (phv00481954.v2.p1)
DONOR_SUBJECT_ID - Donor subject ID (phv00481938.v2.p1)
DRABOMATCH - Donor-recipient ABO type match (phv00481973.v2.p1)
DRCMVPR - Donor-recipient CMV status (phv00481961.v2.p1)
GRAFTYPE - Graft type (phv00481964.v2.p1)
HCTCI - HCT-CI score (continuous) (phv00481960.v2.p1)
HISTOLOGICAL_TYPE - Type of cell or tissue type (phv00482040.v2.p1)
HLAMATCH8 - Is HLA 8/8 match? (phv00481974.v2.p1)
INTDXTX - Time from diagnosis to transplant, months (phv00481955.v2.p1)
INTXAGVHD24 - Time from BMT to grade II-IV acute GVHD, months (phv00481998.v2.p1)
INTXAGVHD34 - Time from BMT to grade III-IV acute GVHD, months (phv00481999.v2.p1)
INTXCGVHD - Time from BMT to chronic GVHD, months (phv00482002.v2.p1)
INTXREL_1Y - Rel/TRM/LFS interval in months at 1 year (phv00481993.v2.p1)
INTXREL_OVERALL - Rel/TRM/LFS interval in months - overall at any timepoint post-BMT (phv00481989.v2.p1)
INTXSURV_1Y - Survival interval in months at 1 year (phv00481985.v2.p1)
INTXSURV_OVERALL - Survival interval in months - overall at any time point post-BMT (phv00481983.v2.p1)
IS_TUMOR - Tumor status of sample (phv00482041.v2.p1)
KPS - Karnofsky performance score (for age >=16) (phv00481959.v2.p1)
LPS - Lansky performance score (for age <16) (phv00481958.v2.p1)
MYELOREG1 - Detailed list of MAC regimens only (phv00481976.v2.p1)
MYELOREG2 - Fewer categories than myeloreg1 (phv00481977.v2.p1)
SAMPLE_ID - Sample ID (phv00482037.v2.p1)
SAMPLE_ID - Sample ID (phv00481930.v2.p1)
SEXMM - Indicates whether donor-recipient sex matched (phv00481970.v2.p1)
SEXMM4 - Donor-recipient sex match, where M-F is male donor, female recipient (phv00481969.v2.p1)
SEXMMDUMMY - Indicates if the donor was female and the recipient was male (phv00481971.v2.p1)
SOURCE_SUBJECT_ID - Subject source ID (phv00481928.v2.p1)
SUBJECT_ID - Subject ID (phv00481937.v2.p1)
SUBJECT_ID - Donor subject ID (phv00481931.v2.p1)
SUBJECT_ID - Subject ID (phv00481925.v2.p1)
SUBJECT_ID - Subject ID (phv00481929.v2.p1)
SUBJECT_SOURCE - Subject source (phv00481927.v2.p1)
TBI - TBI use (phv00481978.v2.p1)
TBIDOSE - TBI dose (cGy) (phv00481981.v2.p1)
TBIFX - TBI fractionated (phv00481980.v2.p1)
YEARTX - Year of transplant (range 2000 to 2020) (phv00481956.v2.p1)
YEARTX_CAT - Year of transplant, categorized by year and cohort (phv00481957.v2.p1)