<p>Children with malignancies, immunodeficiencies, and other life-threatening diseases sometimes receive allogeneic hematopoietic cell transplantation (HCT) as a treatment for their disease.  The HCT process can be complicated by the development of lung disease from infection, alloreactivity, or other causes.  To identify patients at-risk for post-HCT lung disease, this study uses metatranscriptomic RNA sequencing of bronchoalveolar lavage (BAL) obtained prior to HCT.  Sequencing results are associated with the development of post-HCT lung injury. </p>

Metatranscriptomic Sequencing of Pre-Transplant Bronchoalveolar Lavage in    Pediatric Stem Cell Transplant Patients

Hematopoietic Stem Cell Transplantation study with RNA Seq (NGS) data on dbGaP (181 participants)

Selected Publications — phs002208 — Metatranscriptomic Sequencing of Pre-Transplant Bronchoalveolar Lavage in    Pediatric Stem Cell Transplant Patients