This study used the SKBR3 breast cell line and tumor/normal organoids derived from breast tissue to explore the utility of long read sequencing for detecting structural variants in complex samples. Three technologies were used to characterize the samples: Illumina/10X, Pacific Biosciences, and Oxford Nanopore. Methylation results were derived from the Oxford Nanopore data. It is hoped that this resource will better help researchers better understand the utility of long read sequencing in cancer samples.

Comprehensive Analysis of Structural Variants in Breast Cancer Genomes    Using Single Molecule Sequencing

1 selected publication including "Comprehensive analysis of structural variants in breast cancer genomes..." (95 citations)

Comprehensive Analysis of Structural Variants in Breast Cancer Genomes Using Single Molecule Sequencing

Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing