Studies
The Human Pancreas Analysis Program (HPAP)
The Human Pancreas Analysis Program (HPAP)
Request Access
Overview
Selected Publications (9)
Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.
Y. Wang, D. Traum, J. Schug, et al.. (2019). Cell metabolism. Cited 178 times.
https://doi.org/10.1016/j.cmet.2019.01.003
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells
K. Coate, J. Cha, Shristi Shrestha, et al.. (2020). Cell Metabolism. Cited 140 times.
https://doi.org/10.1016/j.cmet.2020.11.006
NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP)
K. Kaestner, A. Powers, A. Naji, et al.. (2019). Diabetes. Cited 133 times.
https://doi.org/10.2337/db19-0058
Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in Type 1 Diabetes
Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, et al.. (2022). Nature metabolism. Cited 126 times.
https://doi.org/10.1038/s42255-022-00531-x
Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D
D. Avrahami, Y. Wang, J. Schug, et al.. (2020). Molecular Metabolism. Cited 76 times.
https://doi.org/10.1016/j.molmet.2020.101057
Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression.
Maria Fasolino, N. Goldman, Wenlian Wang, et al.. (2020). Immunity. Cited 47 times.
https://doi.org/10.1016/j.immuni.2020.01.003
Understanding islet dysfunction in type 2 diabetes through multidimensional pancreatic phenotyping: The Human Pancreas Analysis Program.
Suzanne N. Shapira, Ali Naji, Mark A. Atkinson, et al.. (2022). Cell metabolism. Cited 39 times.
https://doi.org/10.1016/j.cmet.2022.09.013
TCR+/BCR+ dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes
A. S. Japp, Wenzhao Meng, Aaron M. Rosenfeld, et al.. (2021). Cell. Cited 19 times.
https://doi.org/10.1016/j.cell.2020.11.035
Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program
Abhijeet R. Patil, J. Schug, Ali Naji, et al.. (2023). Nature Metabolism. Cited 18 times.
https://doi.org/10.1038/s42255-023-00806-x
