<p>This study reports results from integrative sequencing analyses that combine capture transcriptome sequencing with a comparative analysis of exome capture between the malignant plasma cells and normal cells of patients with relapsed and refractory multiple myeloma (RRMM). This approach has enabled the detection of point mutations, insertions/deletions, gene fusions and rearrangements, amplifications/deletions, and outlier expressed genes among other classes of alterations that contribute to disease progression and drug resistance in the RRMM patients. </p><div><br></div><div><br></div><p></p>

Integrative Genomic and Transcriptomic Analyses of Refractory Multiple    Myeloma

Neoplasms study with RNA-Seq, Targeted-Capture data on dbGaP (511 participants)

Integrative Genomic and Transcriptomic Analyses of Refractory Multiple Myeloma

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