<p>This study was used to perform an exome-limited analysis of whole genome sequencing data of patients with idiopathic pulmonary fibrosis (IPF) or familial pulmonary fibrosis. Case cohorts were derived from local centers at University of Southwestern or Columbia University, and subjects were from the IPFnet cohort of clinical trial. Rare damaging mutations in the coding regions of cases were compared to healthy controls, and gene burden analysis was performed to identify enrichment of novel risk genes in the development of pulmonary fibrosis. </p>

Pulmonary Fibrosis and Telomerase Dysfunction

Idiopathic Pulmonary Fibrosis study with SNP/CNV Genotypes (NGS) data on dbGaP (393 participants)