<p>We investigated single T cell transcriptional states that define donor lymphocyte infusion (DLI) response and resistance from cryopreserved bone marrow mononuclear cells from 15 patients with relapsed chronic myeloid leukemia (CML) after allogeneic hematopoietic stem cell transplant. By integrating bulk ATAC-seq data from sorted T cell populations from these bone marrow samples, we also defined gene regulatory networks that underlay these clusters.</p>

Mapping the Evolution of T Cell States During Response and Resistance to    Adoptive Cellular Therapy

Leukemia, Myelogenous, Chronic, BCR-ABL Positive study with OTHER data on dbGaP (17 participants)