<p>These data are from adult diffuse glioma subjects genotyped on the Illumina OncoArray. Data from this study were used for case control association studies and developing polygenic risk scores. Variants in <a href="https://www.ncbi.nlm.nih.gov/gene/728294">D2HGDH</a> and near <a href="https://www.ncbi.nlm.nih.gov/gene/56975">FAM20C</a> were identified that were associated with glioma subtypes (<a href="https://pubmed.ncbi.nlm.nih.gov/32386320/">PMID: 32386320</a>). Mutation and copy number data are included for select genes and chromosomes. IDH mutation and 1p/19q co-deletion are used in glioma diagnosis and are also prognostic markers. Data for additional prognostic genes and chromosomes are also included. RNA-seq and CHIP-seq data are available for select subjects from this cohort in GEO (<a href="https://www.ncbi.nlm.nih.gov/gds/?term=GSE167806">GSE167806</a>).</p>

Mayo Clinic Adult Diffuse Glioma Illumina OncoArray SNP Data

A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation

Using germline variants to estimate glioma and subtype risks

Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C.