<p>Primary breast tissue, normal and cancerous, was collected immediately after resection. The tissue was dissociated and treated with 10uM tamoxifen or control media for 12 hours in suspension. Single cell libraries were then created using a 10x Genomics gel bead droplet-based kit and sequenced via Illumina sequencing platforms. Differences in cell response to tamoxifen was observed between cell types and distinct responsive and unresponsive cell populations were determined.</p>

Tamoxifen Response at Single Cell Resolution in Estrogen Receptor    Positive Primary Human Breast Tumors

Breast Neoplasms study with RNA-Seq, RNA Seq (NGS) data on dbGaP (13 participants)