<p>MADRES is a prospective pregnancy cohort based in urban Los Angeles, recruiting predominantly low income Hispanic mothers-to-be as part of a children's health study, funded by Environmental Influences on Child Health Outcomes (ECHO). Participants were measured for a number of chemical exposures and biomarkers. Two epigenetic markers will be available through dbGaP: miRNA expression in pregnancy (measured via Nanostring human assay, v3) and DNA methylation from pregnancy and children's cord blood (measured via EPIC array). Principal findings of this research described differences in miRNA expression profiles between early and late pregnancy, as well as miRNA expression affected by psychosocial stress. </p><p> </p>

Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) Center for Environmental Health Disparities

Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study

Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort

Extracellular vesicle-enriched miRNA profiles across pregnancy in the MADRES cohort

Depression, perceived stress, and distress during pregnancy and EV-associated miRNA profiles in MADRES.