<p>To explore the tumor immune microenvironment heterogeneity in sporadic human basal cell carcinoma tumors, we profiled two individual patient tumors by scRNA-Seq. We identified a population of TREM2+ macrophages, which have been implicated in promoting an immunosuppressive tumor microenvironment. We identify that TREM2+ can promote tumor epithelial proliferation in an immunosuppressive independent manner.</p>

TREM2+ Cells in Human Basal Cell Carcinomas

Tumor-Associated Macrophages study with OTHER, RNA Seq (NGS) data on dbGaP (2 participants)