<p>The Sudden Unexplained Death in Childhood Registry and Research Collaborative (<a href="https://sudcrrc.org/">SUDCRRC</a>), created at NYU Langone Health in 2014, connects academic investigators, forensic pathologists, and medical examiner and coroner partner offices to study sudden unexpected pediatric deaths, aged 1 month to 18 years, whose death is unexplained or unclear at the end of the public mandated investigation, including autopsy. Each case includes collection and analysis of all records (medical history from prenatal records throughout life, death scene investigation, autopsy/toxicology/ancillary death investigation reports including photographs and histology slides), biospecimens, and in-depth family interviews. Whole exome sequencing is performed on each deceased child and both biological parents. Additional studies are pursued when indicated by pathology review. Each case receives a multidisciplinary masked review process and parental written consent is obtained. The NYU institutional review board approved this study. </p>

SUDC Registry and Research Collaborative

2 selected publications including "Mosaic mutations in early-onset genetic diseases" (58 citations)

SUDC Registry and Research Collaborative

Mosaic mutations in early-onset genetic diseases

De novo mutations in childhood cases of sudden unexplained death that disrupt intracellular Ca2+ regulation