<p>By leveraging a large-scale collection of stool specimens (Micro-N) within the <a href="https://cedcd.nci.nih.gov/cohort?id=117">Nurses' Health Study II</a>, we performed shotgun metagenomic sequencing and untargeted metabolomics profiling among 121 case women with a diagnosis of diverticulitis requiring antibiotics or hospitalization, with each matched to a control woman without diverticulitis during the same time period accounting for age, race, and month of stool collection (total N=242). We found microbiome and metabolomic profiles differed in diverticulitis cases compared to controls. Data deposited include metagenomic sequencing data (after removing the human sequences) and metabolomics data. </p>

A Prospective Study of Lifestyle, the Gut Microbiome, and Diverticulitis

Diverticulitis study with Metabolomics, WGS data on dbGaP (241 participants)