Chronic Renal Insufficiency Cohort (CRIC) Study Metabolomics and Proteomics

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Anthropometry (4)

BMI - Body Mass Index (kg/m^2) (phv00543541.v1.p1)
HEIGHT - Height (cm) (phv00543539.v1.p1)
WAIST - Waist Circumference (cm) (phv00543543.v1.p1)
WEIGHT - Weight (kg) (phv00543540.v1.p1)

Biomarkers (45)

AFIB - Atrial fibrillation or heart arrhythmia (Yes/Not Yes) (phv00543534.v1.p1)
ALANINE_AMINOTRANSFE - Alanine Aminotransfe (U/L) (phv00543452.v1.p1)
ALBUMINURIA - Urine Albumin (4 Levels) (phv00543554.v1.p1)
ALKALINE_PHOSPHATASE - Alkaline Phosphatase (U/L) (phv00543454.v1.p1)
ASPARTATE_AMINOTRANS - Aspartate Aminotrans (U/L) (phv00543455.v1.p1)
CBCHEMOGLOBIN - CBC Hemoglobin (g/dL) (phv00543549.v1.p1)
CHLORIDE - Chloride (mmol/L) (phv00543457.v1.p1)
CO2 - CO2 (mmol/L) (phv00543523.v1.p1)
CREATININE_SERUM - Creatinine Serum (mg/dL) (phv00543468.v1.p1)
DIASTOLIC - Diastolic BP (mmHg) (phv00543545.v1.p1)
EGFR_CKD_EPI - EGFR - CKD EPI Equation (ml/min/1.73m^2) (phv00543559.v1.p1)
EGFR_CRIC - EGFR - CRIC Equation (ml/min/1.73m^2) (phv00543570.v1.p1)
EGFR_ROCHE - EGFR - ROCHE or MDRD Equation (ml/min/1.73m^2) (phv00543558.v1.p1)
GLUCOSE - Glucose (mg/dL) (phv00543458.v1.p1)
HDL - High-density Lipoprotein (mg/dL) (phv00543449.v1.p1)
HEMATOCRIT - CBC Hematocrit(%) (phv00543550.v1.p1)
HEMOGLOBIN_A1C - Hemoglobin A1C (%) (phv00543459.v1.p1)
LDL - Low-density Lipoprotein (mg/dL) (phv00543450.v1.p1)
MAGNESIUM - Magnesium (mg/dL) (phv00543460.v1.p1)
MAP - Mean Arterial Pressure (phv00543548.v1.p1)
PCR_24HRURINE - Urinary Protein to Creatinine Ratio from 24-Hr Urine Test (phv00543552.v1.p1)
PCR_SPOT - Urine Protein/Creatinine Ratio from spot sample (phv00543574.v1.p1)
PCR_URINE_COMBINED - Urine Protein/Creatinine Ratio, 24Hour and Spot measure combined (phv00543575.v1.p1)
PHOSPHATE_CALIBRATED - Calibrated Phosphate (mg/dL) (phv00543522.v1.p1)
POTASSIUM - Potassium (mmol/L) (phv00543461.v1.p1)
PULSE - Seated pulse measure (beats/min) (phv00543546.v1.p1)
SA_ALLC_ESRD - SurvAn ESRD (phv00543582.v1.p1)
SCR_ROCHE - Roche Adjusted Serum Creatinine (mg/dL) (phv00543557.v1.p1)
SERUM_ALBUMIN - Serum Albumin (g/dL) (phv00543453.v1.p1)
SERUM_UREA_NITROGEN - Serum Urea Nitrogen (mg/dL) (phv00543465.v1.p1)
SODIUM - Sodium (mmol/L) (phv00543462.v1.p1)
SYSTOLIC - Systolic BP (mmHg) (phv00543544.v1.p1)
TC - Total Cholesterol (phv00543448.v1.p1)
TG - Triglycerides (phv00543447.v1.p1)
TOTAL_BILIRUBIN - Total Bilirubin (mg/dL) (phv00543463.v1.p1)
TOTAL_PROTEIN - Total Protein (g/dL) (phv00543464.v1.p1)
UACRATIO - UAlb/UCreat ug/mg (phv00543556.v1.p1)
UALBUMIN24H - 24H Urine Albumin (g/24H) (phv00543553.v1.p1)
UCREATININE24H - 24H Urine Creatinine (g/24H) (phv00543555.v1.p1)
UPROTEIN24H - 24H Urine Protein (g/24H) (phv00543551.v1.p1)
URINE_ALBUMIN - Urine Albumin Concentration (mg/L) (phv00543515.v1.p1)
URINE_CREATININE - Urine Creatinine Concentration from 24-Hour Urine (mg/dL) (phv00543516.v1.p1)
URINE_CREATININE_R - Urine Creatinine Concentration from Random-Spot Urine (mg/dL) (phv00543517.v1.p1)
URINE_PROTEIN_MG_DL - Urine Protein Concentration from 24-Hour Urine (mg/dL) (phv00543466.v1.p1)
UTP_SELECTED_R - Urine Protein Concentration from Random-Spot Urine (mg/dL) (phv00543467.v1.p1)

Demographics (4)

AGE_INTEGER - Age (years) rounded down to the nearest integer (phv00543526.v1.p1)
COLLECTION_AGE - Age sample was collected (phv00543589.v1.p1)
SEX - Sex (1=Male, 2=Female) (phv00543434.v1.p1)
SEX - Biological sex (phv00543427.v1.p1)

Disease Events (14)

ANYCVD - Cardio-Vascular Disease (Yes/Not Yes) (phv00543533.v1.p1)
ARTHRITIS - History of Rheumatoid Arthritis (phv00543572.v1.p1)
ASTHMA - History of Asthma or Reactive Airway Disease (phv00543571.v1.p1)
CHF - Congestive Heart Failure (Yes/Not Yes) (phv00543531.v1.p1)
COPD - History of Chronic Obstructive Pulmonary Disease (emphysema) (phv00543573.v1.p1)
DIABETES - Diabetic Status (phv00543569.v1.p1)
DIABETES_AT_BASELINE - Diabetes at baseline (phv00543444.v1.p1)
FAMILYCAD - Family History of CAD (Yes/Not Yes) (phv00543445.v1.p1)
HYPERTENSION - Hypertension (y/n) (phv00543547.v1.p1)
MIREVASC - MI/Prior revascularization (Yes/Not Yes) (phv00543529.v1.p1)
PVD - Peripheral Vascular Disease (Yes/Not Yes) (phv00543530.v1.p1)
RIGHTABI - Right Ankle Brachial Index (phv00543536.v1.p1)
SA_CHF_D - CHF Definite Status (phv00543576.v1.p1)
SA_DEATH - Death Status (phv00543578.v1.p1)

Environment (1)

LEFTABI - Left Ankle Brachial Index (phv00543537.v1.p1)

General Health (3)

KDQOL_BURDEN - KDQOL: Burden of Kidney Disease (phv00543518.v1.p1)
KDQOL_EFFECTS - KDQOL: Effects of Kidney Disease (phv00543520.v1.p1)
KDQOL_SYMPTOMS - KDQOL: Symptoms/Problems List (phv00543519.v1.p1)

Geography (1)

CCIDSITE - CRIC Clinical Center-Site (phv00543433.v1.p1)

Medications (45)

ACE_INH - Medication Indicator: ACE Inhibitors (phv00543469.v1.p1)
ACEARB - Medication Indicator: ACE Inhibitors or ARBs (phv00543562.v1.p1)
ACTIVE_VITD - Medication Indicator: Active Vitamin D (phv00543488.v1.p1)
ALLOPURINOL - Medication Indicator: Allopurinol (phv00543505.v1.p1)
ALPHA_GLUCO_INH - Medication Indicator: Alpha Glucosidase Inhibitors (phv00543491.v1.p1)
ALPHA2AG - Medication Indicator: Alpha 2 Agonists (phv00543470.v1.p1)
ALPHABLK - Medication Indicator: Alpha Blockers (phv00543471.v1.p1)
ANGIOBLK - Medication Indicator: Angiotensin Receptor Blockers (phv00543472.v1.p1)
ANTIDEPRESSANT - Medication Indicator: Antidepressants (phv00543509.v1.p1)
ANTIDIABETES - Medication Indicator: Anti-Diabetes (phv00543473.v1.p1)
ANTIEPILEPTICS - Medication Indicator: Anti-Epileptics (phv00543503.v1.p1)
ANXIOLYTICS - Medication Indicator: Anxiolytics (phv00543475.v1.p1)
ASPIRIN - Medication Indicator: Aspirin (phv00543510.v1.p1)
BETABLK - Medication Indicator: Beta Blockers (phv00543476.v1.p1)
BIGUANIDE - Medication Indicator: Biguanides (phv00543490.v1.p1)
BILESEQUESTRANTS - Medication Indicator: Bilesequestrants (phv00543507.v1.p1)
BISPHOSPHONATES - Medication Indicator: Bisphosphonates (phv00543500.v1.p1)
BONERI - Medication Indicator: Bone Reabsorption Inhibitors (phv00543499.v1.p1)
CABLK - Medication Indicator: Calcium Channel Blockers (phv00543477.v1.p1)
CALC_PHOSBINDERS1 - Medication Indicator: Calcium-Containing Phosphate Binders (phv00543511.v1.p1)
CALCIFEROLS - Medication Indicator: Calciferols (phv00543513.v1.p1)
CALCIUM - Calcium (mg/dL) (phv00543456.v1.p1)
CORONARY - Medication Indicator: Coronary Vasodilators (phv00543478.v1.p1)
DIGOXIN - Medication Indicator: Digoxin (phv00543506.v1.p1)
DIURETIC - Medication Indicator: Diuretics (all) (phv00543479.v1.p1)
DPP4 - Medication Indicator: DPP4 Inhibitors (phv00543494.v1.p1)
HEPARIN - Medication Indicator: Heparins (phv00543504.v1.p1)
INSULIN - Medication Indicator: Insulin (phv00543480.v1.p1)
KSPARE_DIURETIC - Medication Indicator: Potassium Sparing Diuretics (phv00543481.v1.p1)
LIPID - Medication Indicator: Lipid-Lowering Drugs (phv00543482.v1.p1)
LOOP_DIURETIC - Medication Indicator: Loop Diuretics (phv00543483.v1.p1)
MEGLITINIDE - Medication Indicator: Meglitinides (phv00543493.v1.p1)
NON_CALC_PHOSBINDERS - Medication Indicator: Non-Calcium-Containing Phosphate Binders (phv00543508.v1.p1)
NON_SEL_SRI - Medication Indicator: Non-Selective SRIs (phv00543484.v1.p1)
NSAID - Medication Indicator: NSAIDs (phv00543497.v1.p1)
OTHER_LIPID - Medication Indicator: Lipid-Lowering Drugs (not statins) (phv00543496.v1.p1)
PREDNISONE - Medication Indicator: Prednisone (phv00543512.v1.p1)
SERMS - Medication Indicator: SERMs (phv00543501.v1.p1)
SSRI - Medication Indicator: Selective SRIs (phv00543485.v1.p1)
STATINS - Medication Indicator: Statins (phv00543495.v1.p1)
STEROIDS - Medication Indicator: Steroids (phv00543498.v1.p1)
SULFONYLUREA - Medication Indicator: Sulfonylureas (phv00543489.v1.p1)
THIAZ_DIURETIC - Medication Indicator: Thiazide Diuretics (phv00543486.v1.p1)
TZD - Medication Indicator: Thiazolidinediones (phv00543492.v1.p1)
VASODIL - Medication Indicator: Vasodilators (phv00543487.v1.p1)

Mental Health (2)

BECKS_SCORE - Beck's Depression Index (phv00543567.v1.p1)
MMSE_SCORE - Total score of Modified Mini Mental State Exam: Score (phv00543568.v1.p1)

Race and Ethnicity (6)

BLACK - Black Race (Y/N) (phv00543440.v1.p1)
HISPANIC - Hispanic (y/n) (phv00543436.v1.p1)
RACE_CAT_1 - Race (3 Levels) (phv00543435.v1.p1)
RACE_ETHNICITY - Race Ethnicity (3 Levels) (phv00543437.v1.p1)
RACE_ETHNICITY_CAT2 - Race Ethnicity (4 Levels) (phv00543438.v1.p1)
WHITE - White Race (Y/N) (phv00543439.v1.p1)

Socioeconomic (3)

EDU_CAT_1 - Education Category (7-level) (phv00543442.v1.p1)
INCOME_CAT_1 - Household Income Category (4-level) (phv00543441.v1.p1)
MARSTAT2 - Marital Status Category (3-level) (phv00543443.v1.p1)

Study Administration (1)

FASTING - Fasting before blood draw(y/n) (phv00543525.v1.p1)

Substance Use (3)

ALCOH_USE - Alcohol Use (MedHX) (phv00543535.v1.p1)
SMOKE100 - Smoked 100 Cigarettes (phv00543527.v1.p1)
SMOKENOW - Current Smoker (phv00543528.v1.p1)

Other (33)

ANALYTE_TYPE - Analyte type (phv00543586.v1.p1)
ANTI_ACIDOSIS - Medication Indicator: Anti-Acidosis (phv00543502.v1.p1)
ANTIPLATELET - Medication Indicator: Antiplatelet Drugs (phv00543474.v1.p1)
BODY_SITE - Body site where sample was collected (phv00543585.v1.p1)
BSA - Calculated BSA (md^2) (phv00543542.v1.p1)
CCID - CCID (phv00543432.v1.p1)
CONSENT - Consent group as determined by DAC (phv00543426.v1.p1)
DAYS_THISVISIT - Days from baseline visit to this visit date (phv00543524.v1.p1)
ERYTHROSTIM - Medication Indicator: Erythropoiesis stimulating (phv00543514.v1.p1)
FAMILYRD - Family History of Renal Disease (Yes/Not Yes) (phv00543446.v1.p1)
HISTOLOGICAL_TYPE - Cell or tissue type or subtype of sample (phv00543588.v1.p1)
HVY_MET - Activities with MET scores >=6 (phv00543565.v1.p1)
IS_TUMOR - Tumor status (phv00543587.v1.p1)
LIGHT_MET - Activities with MET scores of < 3 (phv00543563.v1.p1)
LOWABI - Lowest Ankle Brachial Index (phv00543538.v1.p1)
MOD_MET - Activities with MET scores of >=3 to < 6 (phv00543564.v1.p1)
MODHVY_MET - Activities with Met scores >=3 (phv00543566.v1.p1)
NBPCLASS - # Anti-HT Drug Classes Capped at 4 (phv00543561.v1.p1)
NBPDRUGS - # Anti-HT Drug Classes (phv00543560.v1.p1)
SA_ALLC_TIME_ESRD - SurvAn Time to dial/txp (years) (phv00543583.v1.p1)
SA_CVDCOMP3 - CHF(def/prob), MI(def/prob/poss), Stroke(def/prob) Composite Status (phv00543580.v1.p1)
SAMPLE_ID - Sample ID (phv00543584.v1.p1)
SAMPLE_ID - Sample ID (phv00543429.v1.p1)
STROKE - Stroke (Yes/Not Yes) (phv00543532.v1.p1)
SUBJECT_ID - Subject ID (phv00543430.v1.p1)
SUBJECT_ID - Subject ID (phv00543425.v1.p1)
SUBJECT_ID - Subject ID (phv00543428.v1.p1)
TIME_CHF_D - Time to CHF Definite (yrs) (phv00543577.v1.p1)
TIME_CVDCOMP3 - Time to CHF(def/prob), MI(def/prob/poss), Stroke(def/prob) Composite (yrs) (phv00543581.v1.p1)
TIME_DEATH - Time to death (yrs) (phv00543579.v1.p1)
TOTAL_MED - Total number of different medications (phv00543521.v1.p1)
VLDL - Very low-density Lipoprotein (mg/dL) (phv00543451.v1.p1)
VNUM - Visit number, 3=year 0(baseline),5=year 1 (phv00543431.v1.p1)