TARGET Trial Study Cohort

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Anthropometry (1)

BMI - Body Mass Index (phv00543640.v1.p1)

Biomarkers (21)

Cholesterol - Cholesterol (phv00543692.v1.p1)
DBP_MEAN - Diastolic blood pressure (phv00543690.v1.p1)
dm_CD40L - Discovery Map CD40 Ligand (phv00543652.v1.p1)
dm_CRP - Discovery Map C-Reactive Protein (phv00543650.v1.p1)
dm_mmp3 - Discovery Map Matrix Metalloproteinase-3 (phv00543669.v1.p1)
dm_OPG - Discovery Map Osteoprotegerin (phv00543673.v1.p1)
HDL - High Density Lipoprotein (phv00543694.v1.p1)
HIGHCHOL - High cholesterol at baseline, yes or no (phv00543642.v1.p1)
hsCRP - High sensitivity C-reactive protein (phv00543696.v1.p1)
HYPERTENSION - Hypertension at baseline, yes or no (phv00543641.v1.p1)
LDL - Low Density Lipoproetin (phv00543693.v1.p1)
SBP_MEAN - Systolic blood pressure (phv00543691.v1.p1)
v_crp - Vectra C-Reactive Protein (phv00543678.v1.p1)
v_il6 - Vectra Interleuken 6 (phv00543677.v1.p1)
v_MMP1 - Vectra Matrix Metalloproteinase-1 (phv00543680.v1.p1)
v_MMP3 - Vectra Matrix Metalloproteinase-3 (phv00543681.v1.p1)
v_resistin - Vectra Resistin (phv00543682.v1.p1)
v_saa - Vectra Serum Amyloid A Protein (phv00543683.v1.p1)
v_TNF_RI - Vectra Tumor Necrosis Factor Receptor 1 (phv00543684.v1.p1)
v_VCAM1 - Vectra Vascuar Cell Adhesion Molecule-1 (phv00543685.v1.p1)
v_VEGF - Vectra Vascular Endothelial Growth Factor (phv00543686.v1.p1)

Demographics (2)

is_Female - Gender (phv00543630.v1.p1)
SEX - Biological Sex (phv00543626.v1.p1)

Disease Events (2)

DIABETE - Diabetes at baseline, yes or no (phv00543643.v1.p1)
Seropositive - Seropositivity status, rheumatoid factor or anti-CCP positive (phv00543634.v1.p1)

Medications (4)

ASPIRIN - Aspirin use at baseline, daily (phv00543637.v1.p1)
baselineNSAID - NSAID use at baseline, daily or prn (phv00543636.v1.p1)
STATIN_INTENSITY - Statin intensity at baseline, low, moderate, or high (based on standard definitions) (phv00543645.v1.p1)
STEROID - Steroid use at baseline, oral corticosteroid use on a daily basis (phv00543635.v1.p1)

Race and Ethnicity (2)

hispanic - Self reported ethnicity (phv00543632.v1.p1)
RACE_Calc - Self reported race (phv00543631.v1.p1)

Substance Use (1)

SMOKE_Calc - Smoking status at baseline, yes or no (phv00543644.v1.p1)

Other (52)

Aorta - Aorta (phv00543708.v1.p1)
Aorta_MDS - Most Diseased Segment of Aorta (phv00543707.v1.p1)
Bilateral_Carotid - Bilateral Carotid (phv00543706.v1.p1)
CONSENT - Consent group as determined by DAC (phv00543625.v1.p1)
CVRisk - Cardiovascular risk at baseline, any risk factors present (phv00543646.v1.p1)
DAS28_crp - Disease Activity Score 28 with CRP (phv00543698.v1.p1)
dm_adiponectin - Discovery Map Adiponectin (phv00543661.v1.p1)
dm_Apo_AI - Discovery Map Apolipoprotein A-I (phv00543654.v1.p1)
dm_Apo_AII - Discovery Map Apolipoprotein A-II (phv00543655.v1.p1)
dm_Apo_B - Discovery Map Apolipoprotein B (phv00543656.v1.p1)
dm_Apo_CI - Discovery Map Apolipoprotein C-I (phv00543657.v1.p1)
dm_Apo_CIII - Discovery Map Apolipoprotein C-III (phv00543658.v1.p1)
dm_Apo_H - Discovery Map Apolipoprotein H (phv00543659.v1.p1)
dm_ATIII - Discovery Map Antithrombin-III (phv00543664.v1.p1)
dm_cystatinc - Discovery Map Cystatin-C (phv00543671.v1.p1)
dm_il1ra - Discovery Map Interleuken-1 Receptor Antagonist (phv00543651.v1.p1)
dm_il6_binary - Discovery Map Interleuken 6 (phv00543674.v1.p1)
dm_leptin - Discovery Map Leptin (phv00543662.v1.p1)
dm_lox1_binary - Discovery Map Lectin-Like Oxidized LDL Receptor 1 (phv00543676.v1.p1)
dm_lpa - Discovery Map Apolipoproetin(a) (phv00543660.v1.p1)
dm_MIF - Discovery Map Macrophage Migration Inhibitory Factor (phv00543653.v1.p1)
dm_mmp1_binary - Discovery Map Matrix Metalloproteinase-1 (phv00543675.v1.p1)
dm_nt_proBNP - Discovery Map N-terminal prohormone of brain natriuretic peptide (phv00543666.v1.p1)
dm_osteopontin - Discovery Map Osteopontin (phv00543672.v1.p1)
dm_PAI1 - Discovery Map Plasminogen Activator Inhibitor 1 (phv00543665.v1.p1)
dm_resistin - Discovery Map Resistin (phv00543663.v1.p1)
dm_SAA - Discovery Map Serum Amyloid A Protein (phv00543649.v1.p1)
dm_vcam1 - Discovery Map Vascular Cell Adhesion Molecule-1 (phv00543667.v1.p1)
dm_vegf - Discovery Map Vascular Endothelial Growth Factor (phv00543668.v1.p1)
dm_ykl40 - Discovery Map YKL-40 (phv00543670.v1.p1)
final_analysis - Indicator for whether patient was included in main paper analysis, had baseline and follow up MDS TBR (phv00543629.v1.p1)
HAQ_FDI_SCORE - Health Assessment Questionnaire score (phv00543639.v1.p1)
hsTnT - High sensitive troponin T (phv00543697.v1.p1)
Index_Vessel - Index Vessel (phv00543705.v1.p1)
MeanMax_MDS_TBR - Most Diseased Segment of Index Vessel (phv00543704.v1.p1)
MTX_DOSE_WEEKLY - Weekly methotrexate dose at baseline (phv00543638.v1.p1)
RA_DURATION_YRS - Duration of RA disease (phv00543633.v1.p1)
SJC28 - Swollen 28-Joint Count (phv00543699.v1.p1)
subject_global - Subject global disease activity (phv00543701.v1.p1)
SUBJECT_ID - Subject ID (phv00543647.v1.p1)
SUBJECT_ID - Subject ID (phv00543627.v1.p1)
SUBJECT_ID - Subject ID (phv00543688.v1.p1)
SUBJECT_ID - Subject ID (phv00543702.v1.p1)
SUBJECT_ID - Subject ID (phv00543624.v1.p1)
time_period - Visit data was collected at (phv00543648.v1.p1)
time_period - Visit data was collected at (phv00543689.v1.p1)
time_period - Visit data was collected at (phv00543703.v1.p1)
TJC28 - Tender 28-Joint Count (phv00543700.v1.p1)
Triglyceride - Triglyceride (phv00543695.v1.p1)
trt - Treatment group (phv00543628.v1.p1)
v_leptin - Vectra Leptin (phv00543679.v1.p1)
v_YKL40 - Vectra YKL-40 (phv00543687.v1.p1)