<p>We submit data from the TB Aerobiology, Immunology and Transmission (TBAIT) study examining clinical and transcriptomic characteristics associated with Tuberculosis cough aerosolization. From a prospective longitudinal cohort of 142 participants with previously untreated pulmonary <i>Mycobacterium tuberculosis </i>(Mtb) infection, we assessed presence of culturable Mtb aerosols using a cough aerosol sampling system (CASS), as well as other clinical, microbiologic, and immunologic characteristics. We performed whole blood transcriptional profiling (submitted here) on a convenience subset of 29 cough aerosol culture (CAC) positive participants and 29 CAC negative participants, using Illumina NextSeq RNA Sequencing (RNA-Seq). </p>

Aerobiology, Immunology, and Mycobacterium Tuberculosis Transmission

Mycobacterium tuberculosis cough aerosol culture status associates with host characteristics and inflammatory profiles

Tuberculosis Infectiousness is Associated with Distinct Clinical and Inflammatory Profiles