<p>Lung adenocarcinoma in people who have never smoked (NS-LUAD) has a high mortality rate. Knowing NS-LUAD phenotypic plasticity and cell composition can provide guidance for prognosis and treatment. This study comprises large RNA-seq data set from 684 tumor samples from NS-LUAD, including 610 from the <a href="https://dceg.cancer.gov/research/cancer-types/lung/sherlock-lung-study">Sherlock-Lung Study</a> and 74 downloaded from the public <a href="https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bihttps://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000178.v11.p8">TCGA-LUAD data set</a>. We investigate cell dynamics through the transcriptomic data.</p>

Transcriptomic Profiling of Lung Adenocarcinoma From Never-Smokers

A prognostic signature for lung adenocarcinoma in patients who have never smoked.