<p>Single-cell whole genome sequencing (scWGS) provides a tool to gain deeper insights into the clonal relationships of Chr1 copy number changes. Here, we study Chr1 copy number alteration (CNA) using Direct library preparation plus (DLP+), a scalable scWGS platform implemented by image-based object recognition, and open-source computational methods. We report scWGS of 2,046 cells with 400-650 single-cells per patient from 5 Multiple Myeloma patients selected from our biobank with chr1q gains identified by iFISH using a <a href="https://www.ncbi.nlm.nih.gov/gene/1163">CKS1B</a> probe (IRB S21-01218 and I19-01384)</p>

Copy Number Abnormalities of Chr1 in Multiple Myeloma at the Single Cell    Level

Multiple Myeloma study with OTHER data on dbGaP (5 participants)